Specializing in methods, techniques & instruments for chemical, spectral & mass analysis of natural compounds.
Natural Products Chemistry
I am experienced in the various methods, techniques and instruments necessary for chemical, spectral and mass analysis of a wide range of natural products compounds. See pharmcognosy chart.
I have training and experience in lab regulatory issues, lab safety, hazardous materials handling and waste disposal. I can assist your company with new and used equipment resourcing, installation, validation, training, optimization, maintenance and repair. From as little as necessary to as much as you like, I can harness these tools for the benefit of your company.
Botanical Reference Library
Fresh Goldenseal Rhizome & Roots
Leica Low Power Stereo Zoom Sample Inspection Microscope
Clevenger Volatile Oil Traps
Hypericin Solution UV Fluorescence
Goldenseal Adulteration HPTLC
Milk Thistle Extract vs Seed Flavonoids by HPLC
Limonene NIST GC Mass Spectra
3M Petrifilm Yeasts & Molds
J2 Scientific PrepLinc System
TXRF Elemental Spectra
Natural Products Chemistry Experience
1. Classic Pharmacognosy
- Reference Materials
Standard, official and classical texts, reference books, scientific papers.
Significant, statistical and official methods; “Is it a sample or an example?”
Form, appearance, description; for comparison to reference materials and standards.
- Sensory Evaluation
Color, aroma, flavor, texture, etc. Unique identifiers.
Various magnifications and techniques including darkfield, polarized, fluorescence, IR.
- Digital Imaging
Modern cameras and software deliver new levels of analysis, documentation and reporting.
- Classical Methods
Loss on drying, total ash, volatile oils, extractives, foreign matter and much more.
2. Instrumental Analysis
- TLC – Thin Layer (Planar) Chromatography
Scanning Densitometry under UV, Vis, FL.
Everything Camag HPTLC and more.
- LC-Liquid Chromatography
With RI, UV, DAD, ELSD, FL, IT-MS, TQ-MS detection systems.
Agilent (HP / Varian), Perkin-Elmer, Waters, Thermo (Dionex).
- GC – Gas Chromatography
With TCD, FID, ECD, OFD, EI-MS detection systems.
Agilent (HP / Varian), Perkin-Elmer, SRI.
UV, Vis, FL, IR, AA, X-ray, Mass.
Agilent, Perkin-Elmer, Bruker, Hitachi.
3. Specfic Issues
“Health & Safety”
Plate Culture Methods Sanitation Efficiency Total Yeasts & Molds, ATP, Ozone, UV.
Secondary microbiological contamination, UV, TLC, LC-TQMS and Immuno-Affinity methods.
GC-ECD, GC-MS, LC-TQMS + GPC / SPE system. Complete array for routine, wide range, trace analysis.
*Blanket term for insecticides, fungicides, herbicides. etc.
- Residual Solvents
GC-MS, w/ dynamic headspace. Ethanol, Methanol, Butanes, Propane, Acetone and more.
- Elemental Analysis
TXRF, AA + microwave digestion. Mercury, Lead, Cadmium, Arsenic and much more.