EXPERIENCE
Specializing in methods, techniques & instruments for chemical, spectral & mass analysis of natural compounds.
Natural Products Chemistry
I am experienced in the various methods, techniques and instruments necessary for chemical, spectral and mass analysis of a wide range of natural products compounds. See pharmcognosy chart.
I have training and experience in lab regulatory issues, lab safety, hazardous materials handling and waste disposal. I can assist your company with new and used equipment resourcing, installation, validation, training, optimization, maintenance and repair. From as little as necessary to as much as you like, I can harness these tools for the benefit of your company.
Natural Products Chemistry Experience
1. Classic Pharmacognosy
“Qualify”
- Reference Materials
Standard, official and classical texts, reference books, scientific papers. - Sampling
Significant, statistical and official methods; “Is it a sample or an example?” - Macroscopy
Form, appearance, description; for comparison to reference materials and standards. - Sensory Evaluation
Color, aroma, flavor, texture, etc. Unique identifiers. - Microscopy
Various magnifications and techniques including darkfield, polarized, fluorescence, IR. - Digital Imaging
Modern cameras and software deliver new levels of analysis, documentation and reporting. - Classical Methods
Loss on drying, total ash, volatile oils, extractives, foreign matter and much more.
2. Instrumental Analysis
“Quantify”
- TLC – Thin Layer (Planar) Chromatography
Scanning Densitometry under UV, Vis, FL.
Everything Camag HPTLC and more. - LC-Liquid Chromatography
With RI, UV, DAD, ELSD, FL, IT-MS, TQ-MS detection systems.
Agilent (HP / Varian), Perkin-Elmer, Waters, Thermo (Dionex). - GC – Gas Chromatography
With TCD, FID, ECD, OFD, EI-MS detection systems.
Agilent (HP / Varian), Perkin-Elmer, SRI. - Spectroscopy
UV, Vis, FL, IR, AA, X-ray, Mass.
Agilent, Perkin-Elmer, Bruker, Hitachi.
3. Specfic Issues
“Health & Safety”
- Microbiology
Plate Culture Methods Sanitation Efficiency Total Yeasts & Molds, ATP, Ozone, UV. - Mycotoxins
Secondary microbiological contamination, UV, TLC, LC-TQMS and Immuno-Affinity methods. - Pesticides*
GC-ECD, GC-MS, LC-TQMS + GPC / SPE system. Complete array for routine, wide range, trace analysis.
*Blanket term for insecticides, fungicides, herbicides. etc. - Residual Solvents
GC-MS, w/ dynamic headspace. Ethanol, Methanol, Butanes, Propane, Acetone and more. - Elemental Analysis
TXRF, AA + microwave digestion. Mercury, Lead, Cadmium, Arsenic and much more.